Featured Listings

Last Updated: 21/May/2019

The present invention relates to discovery of novel tau-targeted therapeutic drug candidates for the treatment of Alzheimer’s disease (AD).


 

Therapeutic
Neuroscience / Neurology
Early Stage
Government Institute
South Korea
back to top

Last Updated: 21/May/2019

The present invention relates to a pharmaceutical composition for the prevention or treatment of lung fibrosis , comprising stearic acid or its pharmaceutically acceptable salts and antifibrotic agents thereof as an active ingredient.


 

Therapeutic
Fibrosis
Early Stage
Private Corporation
South Korea
back to top

Last Updated: 12/May/2019

The present invention relates to a rapid and background-free lateral flow immunoassay (LFA) platform that utilizes near-infrared (NIR)-to-NIR upconversion nanoparticles (UCNPs)


 

Platform
Diagnostic / Imaging
Early Stage
Government Institute
South Korea
back to top

Last Updated: 12/May/2019

The present invention relates to development of novel vinylsulfone compounds as Nrf2 activator for treatment of Parkinson’s disease (PD).


 

Therapeutic
Neuroscience / Neurology
Early Stage
Government Institute
South Korea
back to top

Last Updated: 12/May/2019

The present invention relates to a method of manufacturing complex nanocage loaded with anthracycline anticancer drug in nanocage produced by the fusion protein of SiRPα and ferritin heavy chain protein.


 

Therapeutic
Oncology
Early Stage
Government Institute
South Korea
back to top

Last Updated: 25/Mar/2019

The present invention relates to a nucleic acid extraction method using a solid subject by forming a complex of a nucleic acid sample and an imidoesters compound in the subject.


 

Diagnostic
Platform
Early Stage
Private Corporation
South Korea
back to top

Last Updated: 18/Oct/2018

This invention provides a pharmaceutical composition for prevention and treatment of the Middle East Respiratory Syndrome (MERS) and an anti-adsorption agent for the Middle East Respiratory Syndrome coronavirus (MERS-CoV)


 

Therapeutic
Infectious Disease
Research
University
South Korea
back to top

Last Updated: 18/Oct/2018

Biomarkers for predicting response to anti-TNF agents Compositions for predicting response to anti-TNF agents Kits for predicting response to anti-TNF agents


 

Diagnostic
Oncology
Research
University
South Korea
back to top

Last Updated: 18/Oct/2018

The present invention relates to a composition for diagnosing neurofibromatosis comprising a genomic DNA-based long PCR primer set and a method for diagnosing neurofibromatosis using the same.


 

Diagnostic
Neuroscience / Neurology
Research
University
South Korea
back to top

Last Updated: 16/Oct/2018

Researher has explored the relationship between PD-1’s receptor, PD-L1 expression and MSI-H gastric carcinomas, to determine if the former could be developed as a potential predictive biomarker in determining the prognosis of patients with this tumor subtype.


 

Diagnostic
Oncology
Research
Private Corporation
South Korea
back to top

Last Updated: 14/Oct/2018

The present invention relates to a patient-specific immunocompetent cell sheet construct consisting of stem cell spheroids through three-dimensional culture technique and the patient’s own histiocytic cells


 

Biomedical
Cell Therapy
Early Stage
University
South Korea
back to top

Last Updated: 14/Oct/2018

The present invention relates to a screening method for inhibiting colorectal cancer by regulating HSPA1L-mediated GP78 and HIF-1α, thereby controlling PrP C levels in colorectal cancer


 

Therapeutic
Drug Discovery / Screening
Research
University
South Korea
back to top

Last Updated: 14/Oct/2018

The present invention relates to an antibody-fluorescent dye conjugate capable of cancer cell-specific fluorescence imaging diagnosis, wherein the fluorescent dye comprises a covalently labelled antibody and is structured to be quenched by interaction with a residue in the antibody, selected from the group consisting ...


 

Diagnostic
Oncology
Early Stage
Government Institute
South Korea
back to top

Last Updated: 14/Oct/2018

On-site pretreatment device capable of pretreatment of high-risk infectious samples without BSL 2 to 4 levels of separate experimental environment cannot be installed POCT and professional experimenter All in One sealed pretreatment device (sample collection + chemical dissolution + mechanical dissolution)


 

Biomedical
Cellular Analysis
Early Stage
Private Corporation
South Korea
back to top

Last Updated: 14/Oct/2018

This invention is an operation method of ocular tumor treatment system with improved safety and an ocular tumor treatment system. An object of the present invention, during treatment of tumors of the eyeball using a proton beam, in the case where the motion range of the eye group more than the set error range, to blo...


 

Medical Device
Ophthalmology
Research
Government Institute
South Korea
back to top

Last Updated: 14/Oct/2018

Consisting of a polysaccharide, a derivative thereof(dextrin, oligosaccharide, hyaluronic acid) and a polyethylene glycol Biocompatible nanoparticle formed by only inter-molecular cross-linking or intra-molecular cross-linking


 

Biomedical
Biomaterial
Research
University
South Korea
back to top

Last Updated: 11/Oct/2018

SphK1 levels could be increased, in both disease types, using either molecular players affecting its expression or via genetic modifications. This increase in turn was found to reverse several of the disease hallmarks seen in the SphK1-deficient conditions.


 

Therapeutic
Neuroscience / Neurology
Early Stage
University
South Korea
back to top

Last Updated: 11/Oct/2018

The researchers achieved a major breakthrough by developing a method for forming CRISPR nanocomplexes consisting of a polymer-derivatized Cas9 protein, and guide RNA that target antibiotic resistance genes.


 

Platform
Gene Therapy
Research
Government Institute
South Korea
back to top

Last Updated: 11/Oct/2018

The researchers demonstrated that expression of these optimized RNA molecules induced immunogenic cell death in cancer cells, but not in non-cancer cells


 

Therapeutic
Immunology
Early Stage
Government Institute
South Korea
back to top

Last Updated: 11/Oct/2018

BEAR presents several advantages over conventional VS methods, in that it depends on the bioactivity data rather than structural information, it facilitates scaffold hopping, and can easily be scaled to screen for thousands of targets.


 

Research
Drug Discovery / Screening
Research
University
South Korea
back to top

Last Updated: 11/Oct/2018

Development of PPI-based anticancer drug using NCAPG2 which is newly identified PLK1 binding protein and the PBD binding structure of PLK1


 

Therapeutic
Oncology
Early Stage
Government Institute
South Korea
back to top

Last Updated: 8/Oct/2018

The present invention relates to a method for constructing metal coordinated complexes with pegylated bilirubin by simple conjugation making amide bond in carboxylate using hydrophilic cloaking agent, PEG (poly ethyleneglycol), and its diverse applications.


 

Platform
Platform
Research
Government Institute
South Korea
back to top

Last Updated: 8/Oct/2018

YE-06 presents as a novel AMPK activator, which could be a promising therapeutic agent for the prevention and treatment of a wide range of age-related metabolic diseases, including diabetes, obesity, and dementia.


 

Therapeutic
Neuroscience / Neurology
Early Stage
University
South Korea
back to top

Last Updated: 8/Oct/2018

The researchers found that administration of BA in mice resulted in decreasing their body weight and fat mass, which was attributed to an increase in energy expenditure when compared to control mice.


 

Therapeutic
Metabolism / Obesity
Research
Private Corporation
South Korea
back to top

Last Updated: 8/Oct/2018

The expression of pyruvate dehydrogenase kinase 2/4 was significantly increased in hindpaw of rats that induced chronic inflammatory pain through complete Freund's adjuvant(CFA) injection and it is associated with painful behavior, hindpaw edema and inflammatory response.


 

Therapeutic
Inflammation
Early Stage
University
South Korea
back to top

Last Updated: 8/Oct/2018

This cell culture techniques promise to revolutionize the field of assisted reproduction and embryo culture, setting new benchmarks for improving successful oocyte preservation and embryo development and selection, and ultimately enhancing the success of assisted reproductive technologies.


 

Biomedical
Reproduction
Early Stage
University
South Korea
back to top

Last Updated: 8/Oct/2018

The present invention provides pharmaceutical compositions comprising sulfonamide compounds such as sulfisoxazole or sulfadoxine for inhibition of cancer cell proliferation, invasion and metastasis.


 

Research
Drug Discovery / Screening
Early Stage
University
South Korea
back to top

Last Updated: 7/Oct/2018

The present invention relates to a method for producing a site-specifically and authentically PTM-modified target protein via new carbon-carbon bond formation


 

Platform
Platform
Research
Government Institute
South Korea
back to top

Last Updated: 7/Oct/2018

The present invention relates to an information processing technique using a computer and especially to technique for calculating an evaluation value regarding an effect of a particular drug on a phenotype of a cancer-cell through a computer simulation using information regarding the cancer-cell and the drug.


 

Research
Drug Discovery / Screening
Research
Government Institute
South Korea
back to top

Last Updated: 7/Oct/2018

The present invention relates to a nucleic acid detection kit and a nucleic acid detection method, which use nanoparticles and, more specifically, to: a nucleic acid detection method comprising a step of amplifying and labeling nucleic acids, and then capturing the same by using nanoparticles and centrifuging the sam...


 

Biomedical
Cellular Analysis
Early Stage
Government Institute
South Korea
back to top

Last Updated: 7/Oct/2018

Our device can reduce the radiation exposure The prototype showed extremely low radiation exposure for intraoperative radiographic localizer In future, the size of radiation generator might be decreased (nanocarbon radiation generator- 1cm diameter)


 

Medical Device
Diagnostic / Imaging
Early Stage
University
South Korea
back to top

Last Updated: 7/Oct/2018

Polyvinyl alcohol (PVA), acetone and the cyanoacrylate are used to facilitate aggregation of samples and solved the difficulty of analysis caused by stained background when staining samples Sine the sample manipulation proceed in a tube, the sample loss is minimal


 

Biomedical
Cellular Analysis
Early Stage
Government Institute
South Korea
back to top

Last Updated: 7/Oct/2018

Conversion method of mesenchymal stromal stem cells to endothelial cells by specific transcription factors


 

Biomedical
Stem Cells
Early Stage
University
South Korea
back to top

Last Updated: 7/Oct/2018

A bone loss inhibitor and therapeutic agent for immunodeficiency diseases comprising RIPK inhibitor as an active ingredient.


 

Therapeutic
Immunology
Early Stage
University
South Korea
back to top

Last Updated: 4/Oct/2018

Activated hepatic stellate cells (HSCs) play a major role in the development of liver fibrosis and their activation is the target of many anti-fibrotic therapies. However, these approaches have remained ineffective mainly due to an incomplete understanding of the molecular mechanisms underlying HSC activation and the...


 

Therapeutic
Fibrosis
Early Stage
University
South Korea
back to top

Last Updated: 29/Sep/2018

The present invention provides a platform that helps predict disease occurrence by using exosomal miRNA profiles in patients in comparison with those in existing patient populations based on databases.


 

Diagnostic
Oncology
Early Stage
University
South Korea
back to top

Last Updated: 29/Sep/2018

The present invention relates to a dicer substrate RNA nanostructure exhibiting enhanced gene silencing effects and a preparation method thereof .


 

Platform
Gene Therapy
Research
University
South Korea
back to top

Last Updated: 28/Sep/2018

It is possible to narrow the operation kit for the filter insertion by using a single wire, and the pain and bleeding complications after venipuncture can be reduced. No need of conventional hook type for fixing, and preventing adhesion to blood vessels, so free to remove the device. Even inexperienced practitioners ...


 

Medical Device
Cardiovascular / Haematology
Early Stage
University
South Korea
back to top

Last Updated: 24/Sep/2018

This invention relates to a device to effectively treat meibomian gland dysfunction that is capable of inducing the discharge of meibomian gland secretion by holding and compressing eyelid while photographing meibomian gland section and diagnosing.


 

Diagnostic
Ophthalmology
Early Stage
University
South Korea
back to top

Last Updated: 24/Sep/2018

As a pharmaceutical composition for preventing or treating cancer comprising keratin, this composition increases the expression of various genes associated with apoptosis, inhibits expression of genes associated with cell proliferation, and inhibits the proliferation of cancer cells, and thus may be usefully used as ...


 

Therapeutic
Oncology
Early Stage
University
South Korea
back to top

Last Updated: 24/Sep/2018

Pharmaceutical composition comprising fluoxetine as an active ingredient for prevention or treatment of central nervous system diseases and vitamin C as an active ingredient for prevention or treatment of central nervous system diseases


 

Therapeutic
Neuroscience / Neurology
Early Stage
University
South Korea
back to top

Last Updated: 21/Sep/2018

Circulating Tumor Cells (CTCs) can be used as a marker for cancer diagnosis, prognosis prediction, and treatment evaluation.


 

Biomedical
Oncology
Early Stage
University
South Korea
back to top

Last Updated: 21/Sep/2018

Using the gene scissors (TALEN) to model the world's first hemophilic disease in degenerated stem cells First mutant gene correction using CRISPR / Cas9 in iPS cells of patients Corrected cells had no nonspecific mutations / Identify the validation in hemophilia mouse model Identify the possibility of c...


 

Therapeutic
Cardiovascular / Haematology
Early Stage
University
South Korea
back to top

Last Updated: 21/Sep/2018

The invention is about composition for preventing or treating a brain injury disease comprising TIM-3 (T-cell immunoglobulin and mucin domain protein 3) inhibitor as an active ingredient, and a screening method for medicine of brain injury disease using TIM-3.


 

Therapeutic
Neuroscience / Neurology
Early Stage
Government Institute
South Korea
back to top

Last Updated: 21/Sep/2018

Thrombin treated stem cell-derived technology for promoting exosome production and enhancing its efficacy


 

Therapeutic
Stem Cells
Early Stage
Private Corporation
South Korea
back to top

Last Updated: 21/Sep/2018

Development of oncolytic adenovirus-based anticancer drugs with both general versatility and selectivity for tumor cells as an organic combination in which the functions of genes are complementary each other


 

Therapeutic
Oncology
Early Stage
University
South Korea
back to top

Last Updated: 9/Jul/2018

• Production of a chimeric antigen receptor (CAR) used for injecting a humanized DR4 antibody gene having apoptosis-inducing activity into a cancer cell-killer T cell • Securing basic technology for the development of dual-acting CAR-T immune cell therapy using CAR-T cell with DR4-specific CAR


 

Therapeutic
Immunology
Early Stage
University
South Korea
back to top

Last Updated: 9/Jul/2018

• Modeling hemophilia in degenerated stem cells using the gene scissors (TALEN) • First mutant gene correction using CRISPR / Cas9 in iPS cells of patients • Corrected cells had no nonspecific mutations and we identified the validation through hemophilia mouse model • Identify the p...


 

Therapeutic
Cardiovascular / Haematology
Early Stage
University
South Korea
back to top

Last Updated: 29/Apr/2018

The technology relates to a single nucleotide polymorphism (SNP) marker for predicting the sensitivity to an anticancer targeted drug, a polynucleotide containing the same, and a method for predicting the sensitivity to a specific anticancer targeted drug.


 

Diagnostic
Oncology
Early Stage
Private Corporation
South Korea
back to top

Last Updated: 27/Mar/2018

This invention is about a flexible electric cautery that burns lesions by supplying high-frequency current to tips from the electrode part.


 

Medical Device
Orthopaedic
Early Stage
Private Corporation
South Korea
back to top