Composition containing melittin for inhibiting tumor-associated M2 macrophages
Date Posted: 24/12/2019
Tumor-associated macrophages are a major component of tumors. Their phenotype is similar to that of M2 macrophages, and they are known to facilitate tumor progression by promoting angiogenesis and immunosuppression. Melittin, a protein derived from bee venom, is cytotoxic to malignant tumor cells, and hence is widely studied for its anti-cancer properties. However, it is unclear how this protein affects immune cells in the tumor environment. For more information, please click here.