Humanized DR4 antibody gene having apoptosis-inducing activity and double-action chimeric antigen receptor-T cell (CAR-T) or natural killer cell (CAR-NK) therapy using the same

Item Number: 583
Industry: Therapeutic
Category: Immunology, Oncology
Development Stage: Early Stage
Organisation Type: University
Country: South Korea
Patent: Korea, PCT
Business Opportunity: Out-Licensing, Technology Transfer, Collaboration R&D


• Production of a chimeric antigen receptor (CAR) used for injecting a humanized DR4 antibody gene having apoptosis-inducing activity into a cancer cell-killer T cell

• Securing basic technology for the development of dual-acting CAR-T immune cell therapy using CAR-T cell with DR4-specific CAR

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