A Novel composition for inhibiting Mycobacterium tuberculosis (Mtb) by modulating macrophage polarity

Item Number: 643
Industry: Therapeutic
Category: Infectious Disease, Respiratory Disease
Development Stage: Early Stage
Organisation Type: University
Country: South Korea
Patent: Korea, PCT, US
Business Opportunity: Out-Licensing, Technology Transfer, Collaboration R&D


The present invention relates to a method to inhibit the survival and proliferation of Mycobacterium tuberculosis (Mtb) by regulating a polarity control of macrophages. More particularly, it includes a composition for inhibiting the survival and proliferation of Mtb by inducing polarization of macrophages through lipopolysaccharide (LPS) and interferon gamma  (IFN-γ).

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