A cell-permeable peptide having a function of blood–brain/spinal cord barrier-penetration, dNP2-congugated ctCTLA-4 protein and a therapeutic agent for central nervous system disorders containing same as an active ingredient

Item Number: 639
Industry: Therapeutic
Category: Neuroscience / Neurology
Development Stage: Early Stage
Organisation Type: University
Country: South Korea
Patent: Korea, PCT
Business Opportunity: Out-Licensing, Technology Transfer, Collaboration R&D


The present invention relates to a cell-permeable peptide having a function of blood–brain barrier (BBB) or blood-spinal cord barrier (BSCB)-penetration, dNP2-congugated cytoplasmic domain of cytotoxic T-lymphocyte antigen 4 (ctCTLA-4) protein. More particularly, it includes its use for treating central nervous system (CNS) diseases using the above peptide.

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