Pharmaceutical composition for preventing and treating cancer, containing malate-aspartate shuttle inhibitor and anticancer drug as active ingredients

Item Number: 635
Industry: Therapeutic
Category: Oncology
Development Stage: Early Stage
Organisation Type: Government Institute
Country: South Korea
Patent: Korea, PCT
Business Opportunity: Out-Licensing, Technology Transfer, Collaboration R&D


The present invention relates to a technology for using a malate-aspartate shuttle (MAS) inhibitor as an agent for treating cancer. More particularly, provided is a pharmaceutical composition for preventing and treating cancer, containing, as an active ingredient, phenyl succinic acid, methyl malonic acid, N-(1-pyrenyl)maleimide and phthalonic acid, which are MAS inhibitors, or a mixture of the MAS and an anticancer drug.

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