Sphingosine kinase 1 (SphK1): Novel therapeutic target for neurodegenerative disease

Item Number: 612
Industry: Therapeutic
Category: Neuroscience / Neurology
Development Stage: Early Stage
Organisation Type: University
Country: South Korea
Patent: Korea, PCT
Business Opportunity: Out-Licensing, Collaboration R&D


SphK1 levels could be increased, in both disease types, using either molecular players affecting its expression or via genetic modifications. This increase in turn was found to reverse several of the disease hallmarks seen in the SphK1-deficient conditions.

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